产品货号：
Z11743
中文名称：
BCAM抗体
英文名称：
Anti-BCAM Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BCAM Antibody |
| 指标别名 | AU;Auberger B antigen;Basal cell adhesion molecule;BCAM;CD239;F8/G253 antigen;LU;Lutheran antigen;MSK19 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | BCAM |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human CD239/BCAM (LLSLTSTLYLRLRKDDRDASFHCAAHYSLPEGRH). |
| 实际分子量 | 85KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Basal cell adhesion molecule,also known as Lutheran antigen,is a plasma membraneglycoprotein that in humans is encoded by the BCAM gene.It is mapped to 19q13.32.This gene encodes Lutheran blood group glycoprotein,a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein,laminin.The protein contains five extracellular immunoglobulin domains,a single transmembrane domain,and a short C-terminal cytoplasmic tail.This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease.Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system.Inactivating variants of this gene result in the recessive Lutheran null phenotype,Lu(a-b-),of the Lutheran blood group.Two transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P50895 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | basal cell adhesion molecule (Lutheran blood group) |
| 蛋白名全称 | Basal cell adhesion molecule |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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